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Mitochondrial fusion is required for spermatogonial differentiation and meiosis
Differentiating cells tailor their metabolism to fulfill their specialized functions. We examined whether mitochondrial fusion is important for metabolic tailoring during spermatogenesis. Acutely after depletion of mitofusins Mfn1 and Mfn2, spermatogenesis arrests due to failure to accomplish a meta...
Autores principales: | Varuzhanyan, Grigor, Rojansky, Rebecca, Sweredoski, Michael J, Graham, Robert LJ, Hess, Sonja, Ladinsky, Mark S, Chan, David C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805159/ https://www.ncbi.nlm.nih.gov/pubmed/31596236 http://dx.doi.org/10.7554/eLife.51601 |
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