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GEMME: A Simple and Fast Global Epistatic Model Predicting Mutational Effects
The systematic and accurate description of protein mutational landscapes is a question of utmost importance in biology, bioengineering, and medicine. Recent progress has been achieved by leveraging on the increasing wealth of genomic data and by modeling intersite dependencies within biological sequ...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805226/ https://www.ncbi.nlm.nih.gov/pubmed/31406981 http://dx.doi.org/10.1093/molbev/msz179 |