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GEMME: A Simple and Fast Global Epistatic Model Predicting Mutational Effects

The systematic and accurate description of protein mutational landscapes is a question of utmost importance in biology, bioengineering, and medicine. Recent progress has been achieved by leveraging on the increasing wealth of genomic data and by modeling intersite dependencies within biological sequ...

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Detalles Bibliográficos
Autores principales: Laine, Elodie, Karami, Yasaman, Carbone, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805226/
https://www.ncbi.nlm.nih.gov/pubmed/31406981
http://dx.doi.org/10.1093/molbev/msz179