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De Novo Mutation Rate Estimation in Wolves of Known Pedigree

Knowledge of mutation rates is crucial for calibrating population genetics models of demographic history in units of years. However, mutation rates remain challenging to estimate because of the need to identify extremely rare events. We estimated the nuclear mutation rate in wolves by identifying de...

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Detalles Bibliográficos
Autores principales: Koch, Evan M, Schweizer, Rena M, Schweizer, Teia M, Stahler, Daniel R, Smith, Douglas W, Wayne, Robert K, Novembre, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805234/
https://www.ncbi.nlm.nih.gov/pubmed/31297530
http://dx.doi.org/10.1093/molbev/msz159