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Size matters: how sample size affects the reproducibility and specificity of gene set analysis

BACKGROUND: Gene set analysis is a well-established approach for interpretation of data from high-throughput gene expression studies. Achieving reproducible results is an essential requirement in such studies. One factor of a gene expression experiment that can affect reproducibility is the choice o...

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Detalles Bibliográficos
Autores principales: Maleki, Farhad, Ovens, Katie, McQuillan, Ian, Kusalik, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805317/
https://www.ncbi.nlm.nih.gov/pubmed/31639047
http://dx.doi.org/10.1186/s40246-019-0226-2