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Does co-transplantation of mesenchymal and spermatogonial stem cells improve reproductive efficiency and safety in mice?

BACKGROUND: Spermatogonial stem cell transplantation (SSCT) is a promising therapy in restoring the fertility of childhood cancer survivors. However, the low efficiency of SSCT is a significant concern. SSCT could be improved by co-transplanting transforming growth factor beta 1 (TGFβ1)-induced mese...

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Detalles Bibliográficos
Autores principales: Kadam, Prashant, Ntemou, Elissavet, Onofre, Jaime, Van Saen, Dorien, Goossens, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805426/
https://www.ncbi.nlm.nih.gov/pubmed/31640769
http://dx.doi.org/10.1186/s13287-019-1420-9