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Ectopic expression of BIRC5-targeting miR-101-3p overcomes bone marrow stroma-mediated drug resistance in multiple myeloma cells

BACKGROUND: Multiple myeloma (MM) cells gain protection against drugs through interaction with bone marrow stromal cells (BMSCs). This form of resistance largely accounts for resistance to therapy in MM patients which warrants further exploration to identify more potential therapeutic targets. METHO...

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Detalles Bibliográficos
Autores principales: Abdi, Jahangir, Rastgoo, Nasrin, Chen, Yan, Chen, Guo An, Chang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805455/
https://www.ncbi.nlm.nih.gov/pubmed/31638931
http://dx.doi.org/10.1186/s12885-019-6151-x