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Robust taxonomic classification of uncharted microbial sequences and bins with CAT and BAT

Current-day metagenomics analyses increasingly involve de novo taxonomic classification of long DNA sequences and metagenome-assembled genomes. Here, we show that the conventional best-hit approach often leads to classifications that are too specific, especially when the sequences represent novel de...

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Detalles Bibliográficos
Autores principales: von Meijenfeldt, F. A. Bastiaan, Arkhipova, Ksenia, Cambuy, Diego D., Coutinho, Felipe H., Dutilh, Bas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805573/
https://www.ncbi.nlm.nih.gov/pubmed/31640809
http://dx.doi.org/10.1186/s13059-019-1817-x