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Therapeutic effect and autophagy regulation of myriocin in nonalcoholic steatohepatitis

BACKGROUND: Ceramide plays pathogenic roles in nonalcoholic fatty liver disease (NAFLD) via multiple mechanisms, and as such inhibition of ceramide de novo synthesis in the liver may be of therapeutically beneficial in patients with NAFLD. In this study, we aimed to explore whether inhibition of cer...

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Detalles Bibliográficos
Autores principales: Yang, Rui-Xu, Pan, Qin, Liu, Xiao-Lin, Zhou, Da, Xin, Feng-Zhi, Zhao, Ze-Hua, Zhang, Rui-Nan, Zeng, Jing, Qiao, Liang, Hu, Chun-Xiu, Xu, Guo-Wang, Fan, Jian-Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805575/
https://www.ncbi.nlm.nih.gov/pubmed/31639005
http://dx.doi.org/10.1186/s12944-019-1118-0