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A framework for TRIM21-mediated protein depletion in early mouse embryos: recapitulation of Tead4 null phenotype over three days
BACKGROUND: While DNA and RNA methods are routine to disrupt the expression of specific genes, complete understanding of developmental processes requires also protein methods, because: oocytes and early embryos accumulate proteins and these are not directly affected by DNA and RNA methods. When prot...
Autores principales: | Israel, Steffen, Casser, Ellen, Drexler, Hannes C.A., Fuellen, Georg, Boiani, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805607/ https://www.ncbi.nlm.nih.gov/pubmed/31638890 http://dx.doi.org/10.1186/s12864-019-6106-2 |
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