Targeting tauopathy with engineered tau-degrading intrabodies

BACKGROUND: The accumulation of pathological tau is the main component of neurofibrillary tangles and other tau aggregates in several neurodegenerative diseases, referred to as tauopathies. Recently, immunotherapeutic approaches targeting tau have been demonstrated to be beneficial in decreasing tau...

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Detalles Bibliográficos
Autores principales: Gallardo, Gilbert, Wong, Connie H., Ricardez, Sara M., Mann, Carolyn N., Lin, Kent H., Leyns, Cheryl E. G., Jiang, Hong, Holtzman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805661/
https://www.ncbi.nlm.nih.gov/pubmed/31640765
http://dx.doi.org/10.1186/s13024-019-0340-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805661/
https://www.ncbi.nlm.nih.gov/pubmed/31640765
http://dx.doi.org/10.1186/s13024-019-0340-6

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