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Retrotransposon gag-like 1 (RTL1) and the molecular evolution of self-targeting imprinted microRNAs

BACKGROUND: Transcription of the antisense strand of RTL1 produces a sense mRNA that is targeted for degradation by antisense microRNAs transcribed from the sense strand. Translation of the mRNA produces a retrotransposon-derived protein that is implicated in placental development. The sense and ant...

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Detalles Bibliográficos
Autores principales: Mainieri, Avantika, Haig, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805670/
https://www.ncbi.nlm.nih.gov/pubmed/31640745
http://dx.doi.org/10.1186/s13062-019-0250-0