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YWHA (14-3-3) protein isoforms and their interactions with CDC25B phosphatase in mouse oogenesis and oocyte maturation

BACKGROUND: Immature mammalian oocytes are held arrested at prophase I of meiosis by an inhibitory phosphorylation of cyclin-dependent kinase 1 (CDK1). Release from this meiotic arrest and germinal vesicle breakdown is dependent on dephosphorylation of CDK1 by the protein, cell cycle division 25B (C...

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Detalles Bibliográficos
Autores principales: Eisa, Alaa A., De, Santanu, Detwiler, Ariana, Gilker, Eva, Ignatious, Alexander C., Vijayaraghavan, Srinivasan, Kline, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805688/
https://www.ncbi.nlm.nih.gov/pubmed/31640562
http://dx.doi.org/10.1186/s12861-019-0200-1