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Prokaryotic Genome Expansion Is Facilitated by Phages and Plasmids but Impaired by CRISPR

Viruses and plasmids can introduce novel DNA into bacterial cells, thereby creating an opportunity for genome expansion; conversely, CRISPR, the prokaryotic adaptive immune system, which targets and eliminates foreign DNAs, may impair genome expansions. Recent studies presented conflicting results o...

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Detalles Bibliográficos
Autores principales: Gao, Na L., Chen, Jingchao, Wang, Teng, Lercher, Martin J., Chen, Wei-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805729/
https://www.ncbi.nlm.nih.gov/pubmed/31681190
http://dx.doi.org/10.3389/fmicb.2019.02254