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Unlocking the therapeutic potential of primary tumor-draining lymph nodes

Lymph nodes draining the primary tumor are essential for the initiation of an effective anti-tumor T-cell immune response. However, cancer-derived immune suppressive factors render the tumor-draining lymph nodes (TDLN) immune compromised, enabling tumors to invade and metastasize. Unraveling the dif...

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Detalles Bibliográficos
Autores principales: Rotman, Jossie, Koster, Bas D., Jordanova, Ekaterina S., Heeren, A. Marijne, de Gruijl, Tanja D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805797/
https://www.ncbi.nlm.nih.gov/pubmed/30944963
http://dx.doi.org/10.1007/s00262-019-02330-y