Phenotypically distinct anti-insulin B cells repopulate pancreatic islets after anti-CD20 treatment in NOD mice

AIMS/HYPOTHESIS: Autoreactive B cells escape immune tolerance and contribute to the pathogenesis of type 1 diabetes. While global B cell depletion is a successful therapy for autoimmune disease, the fate of autoreactive cells during this treatment in autoimmune diabetes is unknown. We aimed to ident...

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Detalles Bibliográficos
Autores principales: Boldison, Joanne, Da Rosa, Larissa C., Buckingham, Lucy, Davies, Joanne, Wen, Li, Wong, F. Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805803/
https://www.ncbi.nlm.nih.gov/pubmed/31444529
http://dx.doi.org/10.1007/s00125-019-04974-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805803/
https://www.ncbi.nlm.nih.gov/pubmed/31444529
http://dx.doi.org/10.1007/s00125-019-04974-y

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