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The BRCA2 mutation status shapes the immune phenotype of prostate cancer

Defects in DNA damage repair caused by mutations in BRCA1/2, ATM or other genes have been shown to play an important role in the development and progression of prostate cancer. The influence of such mutations on anti-tumor immunity in prostate cancer, however, is largely unknown. To better understan...

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Detalles Bibliográficos
Autores principales: Jenzer, Maximilian, Keß, Peter, Nientiedt, Cathleen, Endris, Volker, Kippenberger, Maximilian, Leichsenring, Jonas, Stögbauer, Fabian, Haimes, Josh, Mishkin, Skyler, Kudlow, Brian, Kaczorowski, Adam, Zschäbitz, Stefanie, Volckmar, Anna-Lena, Sültmann, Holger, Jäger, Dirk, Duensing, Anette, Schirmacher, Peter, Hohenfellner, Markus, Grüllich, Carsten, Stenzinger, Albrecht, Duensing, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805809/
https://www.ncbi.nlm.nih.gov/pubmed/31549213
http://dx.doi.org/10.1007/s00262-019-02393-x