Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a mitochondrial disorder that is commonly caused by the m.3243A > G mutation in the MT-TL1 gene encoding for mitochondrial tRNA(Leu(UUR)). While clinical studies reported cerebral infarcts, atherosclero...

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Detalles Bibliográficos
Autores principales: Pek, Nicole Min Qian, Phua, Qian Hua, Ho, Beatrice Xuan, Pang, Jeremy Kah Sheng, Hor, Jin-Hui, An, Omer, Yang, Henry He, Yu, Yang, Fan, Yong, Ng, Shi-Yan, Soh, Boon-Seng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805858/
https://www.ncbi.nlm.nih.gov/pubmed/31641105
http://dx.doi.org/10.1038/s41419-019-2036-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805858/
https://www.ncbi.nlm.nih.gov/pubmed/31641105
http://dx.doi.org/10.1038/s41419-019-2036-9

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