eVIDENCE: a practical variant filtering for low-frequency variants detection in cell-free DNA

Plasma cell-free DNA (cfDNA) testing plays an increasingly important role in precision medicine for cancer. However, circulating cell-free tumor DNA (ctDNA) is highly diluted by cfDNA from non-cancer cells, complicating ctDNA detection and analysis. To identify low-frequency variants, we developed a...

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Detalles Bibliográficos
Autores principales: Mizuno, Kei, Akamatsu, Shusuke, Sumiyoshi, Takayuki, Wong, Jing Hao, Fujita, Masashi, Maejima, Kazuaki, Nakano, Kaoru, Ono, Atushi, Aikata, Hiroshi, Ueno, Masaki, Hayami, Shinya, Yamaue, Hiroki, Chayama, Kazuaki, Inoue, Takahiro, Ogawa, Osamu, Nakagawa, Hidewaki, Fujimoto, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805874/
https://www.ncbi.nlm.nih.gov/pubmed/31641155
http://dx.doi.org/10.1038/s41598-019-51459-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805874/
https://www.ncbi.nlm.nih.gov/pubmed/31641155
http://dx.doi.org/10.1038/s41598-019-51459-4

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