Cargando…

EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells

The EPHB4 receptor is implicated in the development of several epithelial tumors and is a promising therapeutic target, including in prostate tumors in which EPHB4 is overexpressed and promotes tumorigenicity. Here, we show that high expression of EPHB4 correlated with poor survival in prostate canc...

Descripción completa

Detalles Bibliográficos
Autores principales: Sagar, Vinay, Vatapalli, Rajita, Lysy, Barbara, Pamarthy, Sahithi, Anker, Jonathan F., Rodriguez, Yara, Han, Huiying, Unno, Kenji, Stadler, Walter M., Catalona, William J., Hussain, Maha, Gill, Parkash S., Abdulkadir, Sarki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805914/
https://www.ncbi.nlm.nih.gov/pubmed/31641103
http://dx.doi.org/10.1038/s41419-019-2042-y