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The anti-inflammatory agent bindarit acts as a modulator of fatty acid-binding protein 4 in human monocytic cells

We investigated the cellular and molecular mechanisms by which bindarit, a small indazolic derivative with prominent anti-inflammatory effects, exerts its immunoregulatory activity in lipopolysaccharide (LPS) stimulated human monocytic cells. We found that bindarit differentially regulates the relea...

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Detalles Bibliográficos
Autores principales: Oddi, Sergio, Scipioni, Lucia, Totaro, Antonio, Angelucci, Clotilde, Dufrusine, Beatrice, Sabatucci, Annalaura, Tortolani, Daniel, Coletta, Isabella, Alisi, Maria Alessandra, Polenzani, Lorenzo, Assfalg, Michael, Caltagirone, Carlo, Dainese, Enrico, Maccarrone, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805920/
https://www.ncbi.nlm.nih.gov/pubmed/31641194
http://dx.doi.org/10.1038/s41598-019-51691-y