Sequence variants with large effects on cardiac electrophysiology and disease

Features of the QRS complex of the electrocardiogram, reflecting ventricular depolarisation, associate with various physiologic functions and several pathologic conditions. We test 32.5 million variants for association with ten measures of the QRS complex in 12 leads, using 405,732 electrocardiogram...

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Detalles Bibliográficos
Autores principales: Norland, Kristjan, Sveinbjornsson, Gardar, Thorolfsdottir, Rosa B., Davidsson, Olafur B., Tragante, Vinicius, Rajamani, Sridharan, Helgadottir, Anna, Gretarsdottir, Solveig, van Setten, Jessica, Asselbergs, Folkert W., Sverrisson, Jon Th., Stephensen, Sigurdur S., Oskarsson, Gylfi, Sigurdsson, Emil L., Andersen, Karl, Danielsen, Ragnar, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Arnar, David O., Sulem, Patrick, Holm, Hilma, Gudbjartsson, Daniel F., Stefansson, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805929/
https://www.ncbi.nlm.nih.gov/pubmed/31641117
http://dx.doi.org/10.1038/s41467-019-12682-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805929/
https://www.ncbi.nlm.nih.gov/pubmed/31641117
http://dx.doi.org/10.1038/s41467-019-12682-9

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