Tumour-Secreted Hsp90α on External Surface of Exosomes Mediates Tumour - Stromal Cell Communication via Autocrine and Paracrine Mechanisms

Extracellular heat shock protein-90alpha (eHsp90α) plays an essential role in tumour invasion and metastasis. The plasma eHsp90α levels in patients with various cancers correlate with the stages of the diseases. Nonetheless, the mechanism of action by tumour-secreted eHsp90α remained unclear. Here w...

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Detalles Bibliográficos
Autores principales: Tang, Xin, Chang, Cheng, Guo, Jiacong, Lincoln, Vadim, Liang, Chengyu, Chen, Mei, Woodley, David T., Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805946/
https://www.ncbi.nlm.nih.gov/pubmed/31641193
http://dx.doi.org/10.1038/s41598-019-51704-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805946/
https://www.ncbi.nlm.nih.gov/pubmed/31641193
http://dx.doi.org/10.1038/s41598-019-51704-w

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