Induction of tumor-specific CD8(+) cytotoxic T lymphocytes from naïve human T cells by using Mycobacterium-derived mycolic acid and lipoarabinomannan-stimulated dendritic cells

The main effectors in tumor control are the class I MHC molecule-restricted CD8(+) cytotoxic T lymphocytes (CTLs). Tumor-specific CTL induction can be regulated by dendritic cells (DCs) expressing both tumor-derived epitopes and co-stimulatory molecules. Immunosuppressive tolerogenic DCs, having dow...

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Detalles Bibliográficos
Autores principales: Tomita, Yuji, Watanabe, Eri, Shimizu, Masumi, Negishi, Yasuyuki, Kondo, Yukihiro, Takahashi, Hidemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805962/
https://www.ncbi.nlm.nih.gov/pubmed/31531696
http://dx.doi.org/10.1007/s00262-019-02396-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805962/
https://www.ncbi.nlm.nih.gov/pubmed/31531696
http://dx.doi.org/10.1007/s00262-019-02396-8

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