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Oseltamivir Is Effective against 1918 Influenza Virus Infection of Macaques but Vulnerable to Escape

The 1918 influenza virus, subtype H1N1, was the causative agent of the most devastating pandemic in the history of infectious diseases. In vitro studies have confirmed that extreme virulence is an inherent property of this virus. Here, we utilized the macaque model for evaluating the efficacy of ose...

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Detalles Bibliográficos
Autores principales: Feldmann, Friederike, Kobasa, Darwyn, Embury-Hyatt, Carissa, Grolla, Allen, Taylor, Tracy, Kiso, Maki, Kakugawa, Satoshi, Gren, Jason, Jones, Steven M., Kawaoka, Yoshihiro, Feldmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805992/
https://www.ncbi.nlm.nih.gov/pubmed/31641086
http://dx.doi.org/10.1128/mBio.02059-19