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Human V(H)1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis

Staphylococcus aureus is an important human pathogen that infects nearly every human tissue. Like most organisms, the acquisition of nutrient iron is necessary for its survival. One route by which it obtains this metal is through the iron-regulated surface determinant (Isd) system that scavenges iro...

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Detalles Bibliográficos
Autores principales: Bennett, Monique R., Dong, Jinhui, Bombardi, Robin G., Soto, Cinque, Parrington, Helen M., Nargi, Rachel S., Schoeder, Clara T., Nagel, Marcus B., Schey, Kevin L., Meiler, Jens, Skaar, Eric P., Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805997/
https://www.ncbi.nlm.nih.gov/pubmed/31641091
http://dx.doi.org/10.1128/mBio.02473-19