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Human V(H)1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis
Staphylococcus aureus is an important human pathogen that infects nearly every human tissue. Like most organisms, the acquisition of nutrient iron is necessary for its survival. One route by which it obtains this metal is through the iron-regulated surface determinant (Isd) system that scavenges iro...
Autores principales: | Bennett, Monique R., Dong, Jinhui, Bombardi, Robin G., Soto, Cinque, Parrington, Helen M., Nargi, Rachel S., Schoeder, Clara T., Nagel, Marcus B., Schey, Kevin L., Meiler, Jens, Skaar, Eric P., Crowe, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805997/ https://www.ncbi.nlm.nih.gov/pubmed/31641091 http://dx.doi.org/10.1128/mBio.02473-19 |
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