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Molecular Mechanism of SR Protein Kinase 1 Inhibition by the Herpes Virus Protein ICP27

Serine-arginine (SR) protein kinase 1 (SRPK1) catalyzes the phosphorylation of SR proteins, which are a conserved family of splicing factors that contain a domain rich in arginine and serine repeats. SR proteins play important roles in constitutive pre-mRNA splicing and are also important regulators...

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Detalles Bibliográficos
Autores principales: Tunnicliffe, Richard B., Hu, William K., Wu, Michele Y., Levy, Colin, Mould, A. Paul, McKenzie, Edward A., Sandri-Goldin, Rozanne M., Golovanov, Alexander P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805999/
https://www.ncbi.nlm.nih.gov/pubmed/31641093
http://dx.doi.org/10.1128/mBio.02551-19