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Molecular Mechanism of SR Protein Kinase 1 Inhibition by the Herpes Virus Protein ICP27
Serine-arginine (SR) protein kinase 1 (SRPK1) catalyzes the phosphorylation of SR proteins, which are a conserved family of splicing factors that contain a domain rich in arginine and serine repeats. SR proteins play important roles in constitutive pre-mRNA splicing and are also important regulators...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805999/ https://www.ncbi.nlm.nih.gov/pubmed/31641093 http://dx.doi.org/10.1128/mBio.02551-19 |