Antiviral interferons induced by Newcastle disease virus (NDV) drive a tumor-selective apoptosis

Newcastle disease virus (NDV) strongly induces both type I and III antiviral interferons (IFNs-α/-β and IFN-λ, respectively) in tumor cells while it induces mainly type III IFN in normal cells. Impairment of antiviral type I IFN signaling in tumor cells is thought to be the reason for effective onco...

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Detalles Bibliográficos
Autores principales: Ginting, Teridah Ernala, Christian, Salomo, Larasati, Young Othiwi, Suryatenggara, Jeremiah, Suriapranata, Ivet Marita, Mathew, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806003/
https://www.ncbi.nlm.nih.gov/pubmed/31641164
http://dx.doi.org/10.1038/s41598-019-51465-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806003/
https://www.ncbi.nlm.nih.gov/pubmed/31641164
http://dx.doi.org/10.1038/s41598-019-51465-6

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