Metformin restores the mitochondrial membrane potentials in association with a reduction in TIMM23 and NDUFS3 in MPP+-induced neurotoxicity in SH-SY5Y cells

SH-SY5Y cells exposed to 1-methyl-4-phenylpyridinium (MPP(+)) develop mitochondrial dysfunction and other cellular responses similar to those that occur in the dopaminergic neurons of patients with Parkinson's disease (PD). It has been shown in animal models of PD that neuronal death can be pre...

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Detalles Bibliográficos
Autores principales: Chanthammachat, Pitak, Dharmasaroja, Permphan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806136/
https://www.ncbi.nlm.nih.gov/pubmed/31645842
http://dx.doi.org/10.17179/excli2019-1703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806136/
https://www.ncbi.nlm.nih.gov/pubmed/31645842
http://dx.doi.org/10.17179/excli2019-1703

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