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QSAR analysis and molecular docking simulation of norepinephrine transporter (NET) inhibitors as anti-psychotic therapeutic agents

The norepinephrine transporter (NET) is a Na(+)/Cl(−) coupled neurotransmitter transporter responsible for reuptake of released norepinephrine (NE) into nerve terminals in the brain, a key therapeutic used in the treatment of psychiatric disorders. A quantitative structural activity relationship (QS...

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Detalles Bibliográficos
Autores principales: Olasupo, Sabitu Babatunde, Uzairu, Adamu, Shallangwa, Gideon, Uba, Sani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806411/
https://www.ncbi.nlm.nih.gov/pubmed/31692668
http://dx.doi.org/10.1016/j.heliyon.2019.e02640