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A yeast phenomic model for the influence of Warburg metabolism on genetic buffering of doxorubicin

BACKGROUND: The influence of the Warburg phenomenon on chemotherapy response is unknown. Saccharomyces cerevisiae mimics the Warburg effect, repressing respiration in the presence of adequate glucose. Yeast phenomic experiments were conducted to assess potential influences of Warburg metabolism on g...

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Detalles Bibliográficos
Autores principales: Santos, Sean M., Hartman, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806529/
https://www.ncbi.nlm.nih.gov/pubmed/31660150
http://dx.doi.org/10.1186/s40170-019-0201-3