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The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenol-induced Cardiotoxicity

BACKGROUND: Isoproterenol (ISO) is a non-selective β-adrenergic agonist. Our aims were to investigate the autophagy and cell death pathways including apoptosis and necrosis in ISO-induced car-diac injury in a dose-dependent manner. METHODS: Male Sprague-Dawley rats were treated for 24 hours with I....

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Detalles Bibliográficos
Autores principales: Gyongyosi, Alexandra, Zilinyi, Rita, Czegledi, Andras, Tosaki, Agnes, Tosaki, Arpad, Lekli, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806536/
https://www.ncbi.nlm.nih.gov/pubmed/31258063
http://dx.doi.org/10.2174/1381612825666190619145025