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Inflammatory signatures for quick diagnosis of life-threatening infection during the CAR T-cell therapy

BACKGROUND: Chimeric antigen receptor-modified (CAR) T-cell immunotherapy is a novel promising therapy for treatment of B-cell malignancy. Cytokine release syndrome (CRS) and infection are the most common adverse events during CAR T-cell therapy. Similar clinical presentation of concurrent CRS and i...

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Detalles Bibliográficos
Autores principales: Luo, Hui, Wang, Na, Huang, Liang, Zhou, Xiaoxi, Jin, Jin, Li, Chunrei, Wang, Di, Xu, Bin, Xu, Jinhuan, Jiang, Lijun, Wang, Jue, Cao, Yang, Xiao, Yi, Zhang, Qian, Mao, Xia, Liu, Songya, Chen, Liting, Xiao, Min, Zhou, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806557/
https://www.ncbi.nlm.nih.gov/pubmed/31640816
http://dx.doi.org/10.1186/s40425-019-0767-x