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Gene-edited vero cells as rotavirus vaccine substrates

BACKGROUND: Rotavirus (RV) is a leading cause of severe gastroenteritis globally and can cause substantial morbidity associated with gastroenteritis in children <5 years of age. Orally administered live-attenuated RV vaccines offer protection against disease but vaccination efforts have been hamp...

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Detalles Bibliográficos
Autores principales: Orr-Burks, Nichole, Murray, Jackelyn, Wu, Weilin, Kirkwood, Carl D., Todd, Kyle V., Jones, Les, Bakre, Abhijeet, Wang, Houping, Jiang, Baoming, Tripp, Ralph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806661/
https://www.ncbi.nlm.nih.gov/pubmed/31660537
http://dx.doi.org/10.1016/j.jvacx.2019.100045