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Recall Responses from Brain-Resident Memory CD8(+) T Cells (bT(RM)) Induce Reactive Gliosis

HIV-associated neurocognitive disorders (HAND) persist even during effective combination antiretroviral therapy (cART). Although the cause of HAND is unknown, studies link chronic immune activation, neuroinflammation, and cerebrospinal fluid viral escape to disease progression. In this study, we tes...

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Detalles Bibliográficos
Autores principales: Prasad, Sujata, Hu, Shuxian, Sheng, Wen S., Chauhan, Priyanka, Lokensgard, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807101/
https://www.ncbi.nlm.nih.gov/pubmed/31655062
http://dx.doi.org/10.1016/j.isci.2019.10.005