The lipid transfer protein Saposin B does not directly bind CD1d for lipid antigen loading

Background: Lipid antigens are presented on the surface of cells by the CD1 family of glycoproteins, which have structural and functional similarity to MHC class I molecules. The hydrophobic lipid antigens are embedded in membranes and inaccessible to the lumenal lipid-binding domain of CD1 molecule...

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Detalles Bibliográficos
Autores principales: Shamin, Maria, Benedyk, Tomasz H., Graham, Stephen C., Deane, Janet E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807164/
https://www.ncbi.nlm.nih.gov/pubmed/31667358
http://dx.doi.org/10.12688/wellcomeopenres.15368.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807164/
https://www.ncbi.nlm.nih.gov/pubmed/31667358
http://dx.doi.org/10.12688/wellcomeopenres.15368.2

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