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Synthetic Activators of Cell Migration Designed by Constructive Machine Learning

Constructive machine learning aims to create examples from its learned domain which are likely to exhibit similar properties. Here, a recurrent neural network was trained with the chemical structures of known cell‐migration modulators. This machine learning model was used to generate new molecules t...

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Detalles Bibliográficos
Autores principales: Bruns, Dominique, Merk, Daniel, Santhana Kumar, Karthiga, Baumgartner, Martin, Schneider, Gisbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807213/
https://www.ncbi.nlm.nih.gov/pubmed/31660283
http://dx.doi.org/10.1002/open.201900222