Safety of Same-Eye Subretinal Sequential Readministration of AAV2-hRPE65v2 in Non-human Primates

We have demonstrated safe and effective subretinal readministration of recombinant adeno-associated virus serotype (rAAV) to the contralateral eye in large animals and humans even in the setting of preexisting neutralizing antibodies (NAbs). Readministration of AAV to the same retina may be desirabl...

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Detalles Bibliográficos
Autores principales: Weed, Lindsey, Ammar, Michael J., Zhou, Shangzhen, Wei, Zhangyong, Serrano, Leona W., Sun, Junwei, Lee, Vivian, Maguire, Albert M., Bennett, Jean, Aleman, Tomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807311/
https://www.ncbi.nlm.nih.gov/pubmed/31660416
http://dx.doi.org/10.1016/j.omtm.2019.08.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807311/
https://www.ncbi.nlm.nih.gov/pubmed/31660416
http://dx.doi.org/10.1016/j.omtm.2019.08.011

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