Programmed increases in LXRα induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity

OBJECTIVES: Paternally inherited alterations in epigenetic programming are emerging as relevant factors in numerous disease states, including the growth and metabolic defects observed in fetal alcohol spectrum disorders. In rodents, chronic paternal alcohol use induces fetal growth restriction, as w...

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Detalles Bibliográficos
Autores principales: Chang, Richard C., Thomas, Kara N., Bedi, Yudhishtar S., Golding, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807343/
https://www.ncbi.nlm.nih.gov/pubmed/31767168
http://dx.doi.org/10.1016/j.molmet.2019.09.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807343/
https://www.ncbi.nlm.nih.gov/pubmed/31767168
http://dx.doi.org/10.1016/j.molmet.2019.09.016

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