Clinical Considerations for Capsid Choice in the Development of Liver-Targeted AAV-Based Gene Transfer

As gene transfer with adeno-associated virus (AAV) vectors is starting to enter clinical practice, this review examines the impact of vector capsid choice in liver-directed gene transfer for hemophilia. Given that there are multiple clinical trials completed and ongoing in this field, it is importan...

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Detalles Bibliográficos
Autores principales: Pipe, Steven, Leebeek, Frank W.G., Ferreira, Valerie, Sawyer, Eileen K., Pasi, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807344/
https://www.ncbi.nlm.nih.gov/pubmed/31660419
http://dx.doi.org/10.1016/j.omtm.2019.08.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807344/
https://www.ncbi.nlm.nih.gov/pubmed/31660419
http://dx.doi.org/10.1016/j.omtm.2019.08.015

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