2406 The microbial-derived short-chain fatty acid butyrate directly and differentially inhibits gut T helper cell subset activation and proliferation

OBJECTIVES/SPECIFIC AIMS: A hallmark of progressive HIV-1 infection is the massive activation and depletion of the gut barrier protective CD4 T helper subsets (Th17 and Th22) in the intestinal mucosa. The loss of these cells is thought to contribute to microbial translocation and systemic immune act...

Descripción completa

Detalles Bibliográficos
Autores principales: Kibbie, Jon, Dillon, Stephanie, Castleman, Moriah, Liu, Jay, McCarter, Martin, Wilson, Cara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Basic/Translational Science/Team Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807840/
http://dx.doi.org/10.1017/cts.2018.134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807840/
http://dx.doi.org/10.1017/cts.2018.134

Ejemplares similares