A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors

Trypanosoma cruzi carbonic anhydrase (TcCA) has recently emerged as an interesting target for the design of new compounds to treat Chagas disease. In this study we report the results of a structure-based virtual screening campaign to identify novel and selective TcCA inhibitors. The combination of p...

Descripción completa

Detalles Bibliográficos
Autores principales: Llanos, Manuel A., Sbaraglini, María L., Villalba, María L., Ruiz, María D., Carrillo, Carolina, Alba Soto, Catalina, Talevi, Alan, Angeli, Andrea, Parkkila, Seppo, Supuran, Claudiu T., Gavernet, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807911/
https://www.ncbi.nlm.nih.gov/pubmed/31619095
http://dx.doi.org/10.1080/14756366.2019.1677638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807911/
https://www.ncbi.nlm.nih.gov/pubmed/31619095
http://dx.doi.org/10.1080/14756366.2019.1677638

Ejemplares similares