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The Ciliary Muscle and Zonules of Zinn Modulate Lens Intracellular Hydrostatic Pressure Through Transient Receptor Potential Vanilloid Channels

PURPOSE: Lenses have an intracellular hydrostatic pressure gradient to drive fluid from central fiber cells to surface epithelial cells. Pressure is regulated by a feedback control system that relies on transient receptor potential vanilloid (TRPV)1 and TRPV4 channels. The ciliary muscle transmits t...

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Detalles Bibliográficos
Autores principales: Chen, Yadi, Gao, Junyuan, Li, Leping, Sellitto, Caterina, Mathias, Richard T., Donaldson, Paul J., White, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808041/
https://www.ncbi.nlm.nih.gov/pubmed/31639828
http://dx.doi.org/10.1167/iovs.19-27794