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Current understanding and biotechnological application of the bacterial diterpene synthase CotB2

CotB2 catalyzes the first committed step in cyclooctatin biosynthesis of the soil bacterium Streptomyces melanosporofaciens. To date, CotB2 represents the best studied bacterial diterpene synthase. Its reaction mechanism has been addressed by isoptope labeling, targeted mutagenesis and theoretical c...

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Detalles Bibliográficos
Autores principales: Driller, Ronja, Garbe, Daniel, Mehlmer, Norbert, Fuchs, Monika, Raz, Keren, Major, Dan Thomas, Brück, Thomas, Loll, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808215/
https://www.ncbi.nlm.nih.gov/pubmed/31666870
http://dx.doi.org/10.3762/bjoc.15.228