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Site‐Specific Load‐Induced Expansion of Sca‐1(+)Prrx1(+) and Sca‐1(−)Prrx1(+) Cells in Adult Mouse Long Bone Is Attenuated With Age

Aging is associated with significant bone loss and increased fracture risk, which has been attributed to a diminished response to anabolic mechanical loading. In adults, skeletal progenitors proliferate and differentiate into bone‐forming osteoblasts in response to increasing mechanical stimuli, tho...

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Detalles Bibliográficos
Autores principales: Cabahug‐Zuckerman, Pamela, Liu, Chao, Cai, Cinyee, Mahaffey, Ian, Norman, Stephanie C, Cole, Whitney, Castillo, Alesha B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808224/
https://www.ncbi.nlm.nih.gov/pubmed/31667455
http://dx.doi.org/10.1002/jbm4.10199