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Despite Genetic Iron Overload, Hfe‐Hemochromatosis Mice Do Not Show Bone Loss

One of the most prevalent genetic iron overload disorders in Caucasians is caused by mutations in the HFE gene. Both HFE patients and Hfe‐mouse models develop a progressive accumulation of iron in the parenchymal cells of various tissues, eventually resulting in liver cirrhosis, hepatocellular carci...

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Detalles Bibliográficos
Autores principales: Wagner, Alessa, Alan, Betül, Yilmaz, Dilay, Ahmad, Mubashir, Liu, Peng, Tangudu, Naveen Kumar, Tuckermann, Jan P, Vujic Spasic, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808227/
https://www.ncbi.nlm.nih.gov/pubmed/31667458
http://dx.doi.org/10.1002/jbm4.10206