SpliceHetero: An information theoretic approach for measuring spliceomic intratumor heterogeneity from bulk tumor RNA-seq

MOTIVATION: Intratumor heterogeneity (ITH) represents the diversity of cell populations that make up cancer tissue. The level of ITH in a tumor is usually measured by a genomic variation profile, such as copy number variation and somatic mutation. However, a recent study has identified ITH at the tr...

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Detalles Bibliográficos
Autores principales: Kim, Minsu, Lee, Sangseon, Lim, Sangsoo, Kim, Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808416/
https://www.ncbi.nlm.nih.gov/pubmed/31644551
http://dx.doi.org/10.1371/journal.pone.0223520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808416/
https://www.ncbi.nlm.nih.gov/pubmed/31644551
http://dx.doi.org/10.1371/journal.pone.0223520

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