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E2 protein is the major determinant of specificity at the human papillomavirus origin of replication
The replication of human papillomavirus (HPV) genomes requires E1 and E2 proteins as the viral trans-factors and the replication origin, located in the URR, as a cis-element. The minimal requirements for an HPV replication origin vary among different virus types but always include one or more bindin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808437/ https://www.ncbi.nlm.nih.gov/pubmed/31644607 http://dx.doi.org/10.1371/journal.pone.0224334 |