1563. Population Pharmacokinetics and Pharmacodynamics of Daily and Extended Interval Dalbavancin Dosing Regimens for Salvage Therapy of Staphylococcus aureus Endocarditis: Mechanistic Modeling of Rabbit Infection Data to Support Human Dosing Regimens

BACKGROUND: Dalbavancins’ (DAL) long half-life and favorable susceptibility profile makes it an attractive option for salvage therapy for endocarditis caused by Staphylococcus aureus (SA), including those with elevated vancomycin (VAN) MIC. The aim of our study was to establish the PKPD of DAL based...

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Detalles Bibliográficos
Autores principales: Farkas, Andras, Yassin, Arsheena, Fantin, Bruno, Lefort, Agnes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808662/
http://dx.doi.org/10.1093/ofid/ofz360.1427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808662/
http://dx.doi.org/10.1093/ofid/ofz360.1427

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